Diseases Treated With Bone Marrow Transplants -Myelodysplastic syndromes (MDS)

Wat is Myelodysplastic syndromes (MDS)

Myelodysplastic syndromes (MDS) are a group of myeloid stem cell disorders that gradually affect the ability of a person's bone marrow to produce normal cells such as red blood cells, white blood cells, and platelets.

Patients with MDS are at risk of the disease progressing to acute myelogenous leukemia (AML).

The risk of MDS increases with age and most commonly affects people between the ages of 58 to 75. MDS in children is very uncommon.

The exact cause of MDS is not currently known. The progression of events seems to start with a genetic change in the stem cells that are actively dividing to become blood-producing cells. Next, the blood production cells become ineffective, and die off rapidly. Finally, leukemia cells replicate quickly, and AML sets in.

Treatment at Hadassah

Hadassah researchers were among the first in the world to conduct clinical trials in using bone marrow transplantation to treat these diseases, and have achieved a high rate of success in producing cures.

The bone marrow transplant center at Hadassah combines the expertise of many specialties to diagnose and treat these diseases.

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Stem Cell Treatments